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NCPS is concerned with high-alert medications because these drugs are defined as having a higher likelihood of causing injury if misused. tial high-alert medications. During August and September, 2003, more than 350 practitioners responded to an ISMP survey designed to identify which of these medications were most frequently considered high alert by individuals and organiza-tions. Nursing medications in the hospital that must be handled carefully.imrpoves left ventricle dysfunction in acute myocardial infarctionadminister atronpine 0.5mg IV push, repeat 3-5 min if persistsinhibits acetylcholine response relaxing the muscle and increasing the sphincter toneepinephrine in 1m IV push every 3 to 5 minadrenergic agents (epinephrine< isoproterenol, norepinephrine)regular insulin is the only insulin administered IV pushrelated to Paroxysmal Upraventricular Tachicardia (PSTV) caused by affection at the atrioventricular node or at the sinoatrial nodeextravasation is a problem when dopamine is given via peripheral veinrelaxes smooth muscle (bronchodialator) and supresses response of airway stimulusfor heart failure treatment, increases contractility of left ventriclewhen using midazolam monitor vitals (pulse oximetry, have resucitation equipment in the area)High alert medications of the Crash Cart: -----------------------------------------------narcotic accidents are the most frequent and most reportedChloral Hydrate and durgs used for pediatric ambulatory sedation:administered when pH is less than 7.2 for reducing acidosis effects over teh cardiac functionreduces ventricular response in atrial fibrillatioinmetoprolol, atenolol, propanolol, labetalol:administer atropine 1mg IV push, repeat every 305 min is assytole persiststreatment of ventricular arrhythmias and ventricular tachycardiaatropine sulfate (chlorhidrate difenoxilate):errors occur due to toxic nature and are often catastrophicnumber one treatment in sinus bradycardiaacts on atrioventriuclar node for the treatment of atrial fibrillationprescribers often fail to specify the salt levelrespiatory or neurologic depression caused by opiate intoxicationlidocaine 1mg to 1.5 mg times 3 doses as neededdo not allow orders that say "used as needed for agitation"can causes dangerous changes in serum sodium concentrationsphosphate is often given IV as potassium phosphateadminister in all patients with acute coronary syndrome (ACS)verapamil 2.5mg to 5mg every 15 to 30 min times 3 dosesadenosine 3 doses as needed - 6mg IV wait 1-2min > 12mg IV wait 1-2 min > 12 mg IV wait 1-2 min Top Four High Alert Medications 2015, 2016 and 2017 - Central Region (KAMC) 0 50 100 150 200 250 Antithrombotic Agents Opiates/Narcotic Agents Chemotherapeutic Agents Insulin 2015 … The consequences of mistakes with high alert drugs can be devastating. Here are some ways safety can be increased involving the top 5 high alert … adrenergic agents (epinephrine< isoproterenol, norepinephrine) cancer chemotherapeutic agents benzodiazepines intravenous calcium IV heparin thrombolytics and thrombin inhibitors warfarin drugs used for ambulatory pediatric sedation (chloral hydrate, ketamine, midazolam) IV … To learn if you are entitled to seek compensation through a Kentucky injury claim, you would benefit in speaking to a Louisville medication error lawyer as soon as possible.Was Your Child Injured at a Kentucky Daycare? Some high-alert medications also have a high volume of use, increasing the likelihood that a patient might suffer inadvertent harm. ISMP's Top Ten-Ranked High-Alert Medications The top ten-ranked high-alert medications ranked by the 2007 ISMP survey were: Medication % of Respondents Identifying as High-Alert Chemotherapeutic agents, parenteral 97% Neuromuscular blocking agents, such as succinylcholine 94% Epidural or intrathecal medications 93% Insulin, IV 93%

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