Often the cause of the cardiomyopathy is unknown. The condition develops as a result of abnormal genes, which causes the abnormal thickening of the heart muscles. This does not occur in all patients.
Usually the ventricles, the lower chambers of the heart, and septum (the wall that separates the left and right side of the heart) thicken. There are many genes that can cause HCM. The most common cause is coronary artery disease or heart attack.Hypertrophic cardiomyopathy can develop at any age, but the condition tends to be more severe if it becomes apparent during childhood. This results in the heart being less able to pump blood effectively. However some people may find that their symptoms worsen or become harder to control in later life.The area of heart muscle that is affected by hypertrophic cardiomyopathy and the amount of stiffening that occurs will determine how the symptoms affect you.For some people, a number of other conditions can develop as a result of having hypertrophic cardiomyopathy. In some people, however, it's the result of another condition (acquired) or passed on from a parent (inherited).Contributing factors for acquired cardiomyopathy include:Compared with a normal heart, dilated cardiomyopathy causes the chambers of the heart to enlarge, which can lead to heart failure if left untreated.Illustrations of a normal heart (left) and a heart with hypertrophic cardiomyopathy. People with hypertrophic cardiomyopathy also have an abnormal arrangement of heart muscle cells (myofiber disarray). Chronic rapid heart rate 4. This disarray can contribute to arrhythmia in some people.The severity of hypertrophic cardiomyopathy varies widely. Causes and risk factors for hypertrophic cardiomyopathy. Sometimes HNCM will go on to become HOCM.HCM is an inherited condition (a condition that is passed on through families).There’s a 50% (one in two) chance that the children of a parent with hypertrophic cardiomyopathy will also have inherited the risk of developing the disease. Most often diagnosed during infancy or adolescence, hypertrophic cardiomyopathy is the second most common form of heart muscle disease and comprises about 35–40% of cardiomyopathies in children.In familial hypertrophic cardiomyopathy the thickening usually occurs in the interventricular septum, which is the muscular wall that separates the lower left chamber of the heart (the left ventricle) from the lower right chamber (the right ventricle).
This means less oxygen-rich blood is pumped around the body.Changes can also occur in the damaged heart muscle that may trigger problems with the heart's electrical signals, causing an irregular heart beat (arrhythmia).In around one in four people with HCM, the thickening of the heart muscle causes an obstruction which reduces the blood flow from the heart to the body. If you have HCM, your first-degree relatives (parents, brothers, sisters or children) may want to consider screening for the condition.Some people with HCM have no symptoms and their condition may go undiagnosed for a long time. Never stop taking your medication without talking to your doctor first. The left ventricle (one of your heart’s four chambers) is almost always affected, and in some people the muscle of the right ventricle also thickens.Hypertrophic cardiomyopathy often goes undiagnosed because many people with the disease have few, if any, symptoms and can lead normal lives with no significant problems. Hypertrophic cardiomyopathy is an inheritable disease.
It’s this layer that is affected by cardiomyopathy.
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