Ebony J Adams, Pharm.D, Lindsey B Amerine, Pharm.D., M.S., BCPS, Process improvement strategy to prepare and administer bacillus Calmette-Guérin vaccine in compliance with United States Pharmacopeia chapter 800 standards, American Journal of Health-System Pharmacy, Volume 76, Issue 9, 1 May 2019, Pages 613–616, https://doi.org/10.1093/ajhp/zxz027. BCG VACCINE for percutaneous use, is an attenuated, live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis.1 The TICE® strain used in this BCG VACCINE preparation was developed at the University of Illinois from a strain originated at the Pasteur Institute. Bacillus Calmette–Guérin (BCG) into Three Equal (1/3) Doses) and administered to patients already in the facility ready for their treatment. 0000000016 00000 n Don't already have an Oxford Academic account? 137 Introduction 139 General considerations 139 Special considerations 140 Scope of the Recommendations 141 BCG vaccine strains 141 Potency-related tests 142 Part A. Author summary Mycobacterium tuberculosis has been causing infections in our species and our ancestors for at least thousands of years. Search for other works by this author on: © American Society of Health-System Pharmacists 2019. %%EOF 0000006834 00000 n 0000001487 00000 n 0000030091 00000 n x�b```�8V�� cc`a��`���}e�b:���hϰ���������&����]�3��,�}�ōaLA���C*�(8�0r�Xp�PYp֦��g"P�WF)4r� �����6�3��Y�C�`�;���@���s��,� �3g^��8+���t���3�� �����bKk �LJ�`�C�`�`qqq�r��,��(���b� ҡ�� T���vH���T��0�ܠ0A�30�v3�1�`��1�_�����Ėj�"9e��L ��FlI�!� �\@�4�\F�Ɔy�NL����L v Y8(d`^~H#��H�10��ҚbFpU���g�|�? 3�;���Z�|KWB�u��:��"w��Vn����n A�Y���9gw��_{Ԏ,vO;����*`1�����b�k�Z(m��.i���lo�e��46��x'��ŰG�F��W�� 0 � 0000030945 00000 n hޜ�wTT��Ͻwz��0�z�.0��. You could not be signed in. endobj 0000000756 00000 n 0000003348 00000 n �� Most users should sign in with their email address. ���`��7�`� �Jku��䯍ډ�R�b���o*�پUQd��aK�ķY��gY�J7���$�2��l5:0]�=�����Ow��B�hQp|m�NP�,�5�F�ThY�M��a��:�Z��܈;e�To>x�KT֘�u���+P(���]ڠ+۪��vCMT��3�)�(TE���k���h^(���XC>JH��8JO�Z"b���1�h�e��Lkc)��g���'��d=Zd����c�ї��7��,���c�� &9K�J�ha��w�iªM�d [IJ�8+YYH�d��>�杈c@�f�aO�8P��?ßP��ZZ:N�� @��������{v�����=,�/��oh�"�.Κ�ߗ�7��-�]��h%e�&e�{�w��p��u�~]�� ���w�`~�=�p���f��݇�����n(�e��=.++E������6�uo6:�W� �glH�i:��TQ���AŨ;Tڛ�&"۬����wY头�˷���FCm��. 2 0 obj Bacille Calmette-Guerin vaccination is a live, attenuated vaccine derived from M. bovis. 186 0 obj <>stream 0000006553 00000 n �������n�9����ݹC�-��~R���0P5V�C�`b5��H���X��=+����(r�̄_8�/uk����0�{x.���`U��Fkr3��R�+�zV�1�CM�`Oq.�)ah�x����y���m�4�tidy�n�f��ҞjTH�:mw�u'���c�� �7"��Jqm�5Kw��F%EC'5:�gJ��"CtƣЮ̎A���MEve�9M릋�O�čH�y�Ŕ�lp���c�g��$�9��J�TAu��+��i�$|�b?��\z������&|^�X��)�IֱSt�2|�U}mn��B�|-ѥ��dTg�A��#�2(���DIEr۞��C1�r2�Z�t�;9� ��k���-�����ϣ�B= ua�r|l.�t�m�.V���ʁ �iN�X'����33�`H�hi�Ͳ� ��I��Xޑ�w���,�Yw���qO����a�H�A�hR�l�V�����qSә�"���A���*���͊&�o��%��M��q_����*����� �T����v�\��u]�}��ΝɻD�K��n��kKtg�N:_����u�q� Kt�N�j�`��m%c�K��TZ�5����d�����_���Js�n����E��V�R��ƺ���N��[S�������u�u��8}c�ͣ��h�Y�j�pQ� u�tUO�Q2 Decontamination before admixing non-cytotoxics If you originally registered with a username please use that to sign in. Through a multidisciplinary initiative involving pharmacists, physicians, nurses, and leadership, a new process to promote the safe preparation and administration of the tuberculosis vaccine Mycobacterium bovis BCG was developed and implemented. BCG is routinely given at birth in the majority of countries with an intermediate or high incidence of TB. It is one of the most widely used yet controversial modern vaccines. endobj Please check your email address / username and password and try again. the preparation of BCG and prepare chemotherapeu-tic agents in a separate pharmacy location.1 Other centres prepare BCG on the ward using a contain-ment device. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide, This PDF is available to Subscribers Only. %PDF-1.6 %���� Approximately 100 million children receive BCG annually throughout the world. 0000001714 00000 n Leftover BCG must NOT be saved for future patients 15. dispose of all supplies used to reconstitute BCG as biohazardous waste according to site-specific policies and procedures Note: 0000003884 00000 n 0000003252 00000 n 0000002316 00000 n 4 0 obj 0000001337 00000 n Please check for further notifications by email. �&rr �3�c ҳ3�Z���`�O����=�"��D�E �T,C[����S �� �4J~�[��N�0) �c��R�PPN���7p�R2|���>u������CۂWyhQ�O-!.��ؓNr The results of a post-implementation time study indicated that a standardized approach to scheduling, preparing, and administering BCG …
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